Frequently Asked Questions

We only use the sequences to perform the requested annotation, and use that to compute the displayed plots.

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This plot shows the alignment of the query sequence to the best scoring V gene segment and J gene segment. The features above the alignment show the complementarity determining regions (CDRs), which typically interact with the antigen to determine binding. Additional features below the alignment can provide descriptors of the query sequence itself, e.g., charge, hydrophobicity, etc.

The example alignment below shows the Adalimumab heavy chain.